primary ovarian insufficiency/protease

The reproductive organs are unique among adult organs in that they must undergo continual tissue remodelling as a key aspect of their normal function. The processes for persistent maturation and release of new gametes, as well as fertilisation, implantation, placentation, gestation and parturition

The assembly of the developmentally arrested primordial follicle and subsequent transition to the primary follicle are poorly understood processes critical to ovarian biology. Abnormal primordial follicle development can lead to pathologies such as premature ovarian failure. The current study used a

Study question: Do human granulosa cells (GCs) ingest and destroy apoptotic oocytes? Summary answer: Somatic GCs ingest and destroy apoptotic oocytes and other apoptotic