pronuciferine/nelumbo nucifera

OBJECTIVE To establish an HPLC method for the determination of four alkaloids, i.e., 2-hydroxy-1-methoxyaporphine, pronuciferine, nuciferine and roemerine, in Nelumbo nucifera and its alkaloid fraction. METHODS The determination was carried out at 35 degrees C on a Hypersil C18 column (4.6 mm x 250

OBJECTIVE To isolate and identify pronuciferine monomer. METHODS The primary compositions in the seed of Nelumbo nucifera were extracted by supercritical CO2 way, then isolated and purified by column chroatography fractionation and identified by HPLC, TLC, GC-MS. RESULTS A monomer was further

Blood-brain barrier (BBB)-permeable components in the methanolic extract of Nelumbo nucifera flowers showed accelerative effects on neurite outgrowth in PC-12 cells. Among the constituents isolated from N. nucifera flowers in our previous study, aporphine-type alkaloids, lirinidine, asimilobine,

OBJECTIVE Nelumbo nucifera (Gaertn.) leaves are used widely in modulating obesity in traditional Chinese medicine. Our previous work demonstrated that aporphine alkaloids from it increased the glucose consumption in mature 3T3-L1 adipocytes. However, the underlying mechanisms of this increase remain

Aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn are substances of great interest because of their important pharmacological activities, particularly anti-diabetic, anti-obesity, anti-hyperlipidemic, anti-oxidant, and anti-HIV's activities. In order to produce large amounts of pure

Lotus leaves are a popular remedy in Asia to treat obesity, insomnia and mental impairment; alkaloids are considered most relevant for bioactivity. In this study the first CE method for the determination of all major alkaloids ((-)-nuciferine, (-)-nornuciferine, (-)-caaverine, (-)-armepavine,

A quantitative analytical method for five aporphine alkaloids, nuciferine (1), nornuciferine (2), N-methylasimilobine (3), asimilobine (4), and pronuciferine (5), and five benzylisoquinoline alkaloids, armepavine (6), norarmepavine (7), N-methylcoclaurine (8), coclaurine (9), and norjuziphine (10),

Six alkaloids were isolated from the green seed embryo of Nelumbo nucifera growing in Ruichang, Jiangxi province. On the basis of physiochemical properties and spectroscopic methods (UV, IR, NMR, MS) they were identified as: lotusine, nuciferine, pronuciferine, liensinine, isoliensinine and