protease/necrosis

CROSS REFERENCE TO RELATED APPLICATION This application is a National Stage of International Application No. PCT/KR2011/009914 filed Dec. 21, 2011, claiming priority based on Korean Patent Application No. 10-2010-0132955 filed Dec. 23, 2010, the contents of all of which are incorporated herein by

CROSS REFERENCE TO RELATED APPLICATIONS This application is a National Stage of International Application No. PCT/KR2010/007160 filed on Oct. 19, 2010, which claims priority from Korean Patent Application No. 10-2009-0099219, filed on Oct. 19, 2009, the contents of all of which are incorporated

FIELD OF THE INVENTION The present invention relates to proteases involved in apoptosis signalling pathways, to processes for the purification of the proteases, and more particularly to methods for the use of the proteases to modulate apoptosis in target cells. BACKGROUND OF THE INVENTION Necrosis

FIELD OF THE INVENTION This invention relates to the use of cyclic peptides for modulating cytokine activity, including signaling and inflammatory pathways, in various diseases. More particularly, cyclic peptides possess hereto unknown biological activities, such as inhibition of sheddases and other

BACKGROUND OF THE INVENTION 1. Technical Field of the Invention This invention relates generally to cytoenzymology, and more particularly to methods and reagents used in cytoenzymology. 2. Discussion of the Background Art Apoptosis, or programmed cell death, is a process that involves the activation

1. INTRODUCTION The present invention relates to improved methods and compositions for the collection of placental stem cells, e.g., by perfusion or physical and/or enzymatic disruption of a placenta or a part thereof, and methods of collecting the stem cells using the compositions. The compositions

1. INTRODUCTION The present invention relates to improved methods and compositions for the collection of placental stem cells, e.g., by perfusion or physical and/or enzymatic disruption of a placenta or a part thereof, and methods of collecting the stem cells using the compositions. The compositions

FIELD OF THE INVENTION This invention relates to secretion of heterologous bioactive proteins, in particular, granulocyte macrophage colony stimulating factor ("GM-CSF") by an expression system inserted into a host selected from the Streptomyces genera. BACKGROUND OF THE INVENTION In producing

The present invention relates to de novo compositions of matter for the treatment of AIDS. The present invention further relates to the de novo compositions of matter containing TNF inhibitors and antiviral agents selected from the group of reverse transcriptase inhibitors, protease inhibitors, gene

FIELD OF THE INVENTION The invention relates generally to polypeptides involved in the regulation of bone metabolism. More particularly, the invention relates to a novel polypeptide, termed osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily. The polypeptide is used

FIELD OF THE INVENTION The invention relates to the field of metalloproteases. Specifically, the invention relates to activation or inhibition of the ADAM family of proteases. More specifically, the invention relates to activation or inhibition of the TNF-.alpha. converting enzyme (TACE). BACKGROUND