ptaquiloside/edema

Single subcutaneous injections of 5 and 10 mg/kg of braxin C (BC), ptaquiloside, a toxin isolated from bracken fern, have been shown to induce hemorrhagic cystitis in guinea pigs. In order to determine whether the hemorrhagic cystitis induced by BC is due to the urotoxic effects or not, BC was

Braxin C (BC), ptaquiloside, is a toxin isolated from bracken fern. In order to determine the characteristics of the acute BC toxicity, BC was administered as a single subcutaneous (s. c.) injection to guinea pigs, rats, and mice. BC (5 and 10 mg/kg) induced hemorrhagic cystitis and hematuria in