scoparone/angelica

OBJECTIVE To study the chemical constituents of the root of Angelica dahurica cv. Qibaizhi. METHODS The compounds were isolated and purified by the methods of solvent extraction and chromatographic technique, and their structures were identified on the basis of the analyses of spectral

A rapid and sensitive reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed to investigate pharmacokinetics of columbianadin, one of the main bioactive constituents in the roots of Angelica pubescens f. biserrata, in rat plasma after intravenous administration to rats

1. More than 300 coumarins have been identified from natural sources, especially green plants. The pharmacological and biochemical properties and therapeutic applications of simple coumarins depend upon the pattern of substitution. More complex related compounds based on the coumarin nucleus include

OBJECTIVE To use structure-activity analysis to study the anti-Alzheimer's disease (anti-AD) activity of natural coumarins isolated from Angelica decursiva and Artemisia capillaris, along with one purchased coumarin (daphnetin). METHODS Umbelliferone, umbelliferone 6-carboxylic acid, scopoletin,