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Pathophysiological effects following biliary tract reconstruction for benign biliary diseases were investigated from the standpoint of gastric acid secretion, metabolism of nutrients and gastrointestinal hormone release. Patients undergoing Roux-Y hepaticojejunostomy showed a significant increase in
1. The content and distribution of carbohydrate was examined in mucus glycopolypeptides from human antral mucosae. 2. The mean amount of carbohydrate per 1000 amino acid residues was found to be similar in glycopolypeptides with A, B or H activity. It was slightly, though significantly, less in
The results of the study made in 43 patients with gastroduodenal ulcer have shown an increase in the production of proinflammatory cytokines (interleukin-1 beta, the tumor necrosis factor-alpha) and a decrease in the blood serum content of the transforming growth factor-beta, which events come to
Examination of 84 patients with peptic ulcer of the duodenum demonstrated that the majority of patients had alterations in carbohydrate metabolism manifested by fasting hypoglycemia, slow increase in glucose and hyperglycemia at the 180th minute during making the glucose tolerance test. The level of
Activity of the main enzymes of pentose phosphate pathway of carbohydrate metabolism was studied in human mucosa of the stomach. In the mucosa glucose-6-phosphate dehydrogenase in gastric ulcer and 6-phosphogluconate dehydrogenase in normal stomach were shown to be less active as compared with these
The duration of gastric impairment before perforation as well as morphological features of sutured ulcer were shown to influence the protective functions of the gastric and duodenal mucosal membrane as shown by estimation of hexose, fucose and sialic acids in the blood serum and urine of 128
Levels of gexosamines, free oxiprolin, gexuronic acids, malonic dialdehyd, reduced glutathione and total content of gexosamines in blood as well as spontaneous chemiluminescence of blood serum were studied in 89 patients with duodenal ulcer during rehabilitative treatment and in 35 healthy subjects.