stomach ulcer/protease

Study of the spectrum of acid proteases of dog gastric juice secreted in response to different stimuli in health and atophan gastric ulcer has shown that gastric juice may contain up to 17 proteases as evaluated from relative electrophoretic mobility of protease fractions. In individually taken

In combination with routine gastric secretion test and endoscopic congo red test, alkali labile pepsin (ALP) and alkali stable pepsin (ASP) were separately determined in total of 41 patients with peptic ulcer including 20 gastric (GU), 12 duodenal (DU) and 9 gastroduodenal ulcers (GDU), and in 10

Using a simple hemoglobin method on the basis of Anson-Mirsky's method, acid protease levels in serum were measured at pH 1.8 (pepsin) and pH 3.5 (gastricsin) in 18 healthy controls and 14 patients with duodenal ulcer, 19 patients with gastric ulcer and 18 patients with gastric cancer. Though acid

Proteases play a pivotal role in many signaling pathways; inhibitors of well-established proteases have shown a substantial therapeutic success. This study aimed to examine the in vivo effects of 3 protease inhibitors isolated from Bauhinia species: i) Bauhinia mollis elastase

Patients with duodenal ulcers were examined for the degree and duration of the effect of almagel, gastrocepin and food on pH and protein digestion by various enzymes of the contents of the stomach and initial part of the duodenum. Acidity and protein digestion were determined in vitro with 3 values

ADAM metallopeptidase domain (ADAM)9, 10 and 17 have α-secretase activity that regulates ectodomain shedding of factors involved in inflammation, cell proliferation, angiogenesis, and wound healing. The secretase activity of ADAM proteins is known to induce an inflammatory response. However, under

This study evaluates the biochemical interactions between two widely used anticoagulants agents, Aspirin and Warfarin, with the Pepsin as the main stomach protease. These two drugs usually prescribe orally for long period daily use to reduce cardiovascular and thrombi death which leads to being in

Glycoproteins are major constituents of the two-component mucous barrier: glycoproteins of the mucin-type rich in carbohydrate groups form the viscoelastic mucous gel of the mucosa, oligosaccharides of glycoproteins and glycosphingolipids embedded into the plasma membrane form the glycocalyx of the

On the model of peptic ulcer the mechanisms of interrelations between salivary glands and stomach have been proved. Activation of proteolysis which took place together with a decrease in the activity of alpha 1--inhibitor for proteases in lipid peroxidation (LPO), and an increase in depolymerization

Recent studies have suggested the possible involvement of the kallikrein-kinin cascade in gastric inflammatory diseases and malignant transformation in peptic ulcers. Germ-line mutations of genes responsible for repairing DNA mismatch may cause the transformation of chronic peptic ulceration to

Based on the results of 11200 endoscopies of the stomach and duodenum, the incidence of peptic ulcer in children was established with regard to the sex and site of ulcer. The authors view peptic ulcer as a heterogeneous disease in terms of the genealogical data and differences in proteolytic

Acid proteolytic zymogens contained in biopsy specimens obtained from the area surrounding peptic ulcers of the stomach were analyzed by means of agar gel electrophoresis and compared with histopathological findings. It was demonstrated that the specimens obtained from the base of ulcer contained