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TECHNICAL FIELD
This invention relates to benzenesulfonic acid salt or benzoic acid salt of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid which is excellent in antihistaminic activity and antiallergic activity, a process for preparing the same, and an optically resolving
TECHNICAL FIELD
This invention relates to benzenesulfonic acid salt or benzoic acid salt of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid which is excellent in antihistaminic activity and antiallergic activity, a process for preparing the same, and an optically resolving
FIELD OF THE INVENTION
This invention relates to novel substituted N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones and non-toxic acid addition salts thereof, to methods of preparing these compounds, to pharmaceutical composition containing them as active ingredients, and to methods of using them
This invention relates to novel use of a compound of the formula: ##STR2## wherein R.sub.1 and R.sub.2 are each hydrogen or methyl, providing that when R.sub.1 is hydrogen, R.sub.2 is hydrogen.
More particularly, it relates to use of the compound (I) as antiallergic agent for prophylaxis and therapy
FIELD OF INVENTION
The present invention relates to pharmaceutical compositions effective for preventive and/or therapeutic treatment of allergic diseases such as pollinosis, bronchial asthma, atopic dermatitis, urticaria; endometriosis, and hysteromyoma.
BACKGROUND ART
Allergic diseases are
This invention relates to novel substituted acetamide compounds having an anti-allergic activity and being useful as an anti-allergic agent. More particularly, it relates to substituted acetamide compounds of the formula: ##STR3## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a lower acyl
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is based upon PCT Application Ser. No. PCT/EP 94/02287, filed Jul. 6, 1994, which claims priority from European Patent Application Ser. No. 93.202.154.6, filed on Jul. 13, 1993.
WO 92/22 551 and WO 92/22 553 describe imidazoazepines having
This invention relates to azepinoindoles, their production and pharmaceutical compositions containing them.
The present invention provides 1,2,3,4,5,6-hexahydro-6-phenyl-azepino[4,5-b]indoles or pharmaceutically acceptable acid addition salts thereof hereinafter referred to as compounds of the
BACKGROUND OF THE INVENTION
In U.S. Pat. Nos. 4,556,660; 4,634,704; 4,695,569; 4,695,575; 4,588,722; 4,835,161; 4,897,401 and in EP-A-0,206,415 and 0,297,661 there are disclosed related furanyl and/or alkylfuranyl derivatives as antihistaminics and serotonin antagonists.
DESCRIPTION OF THE
This invention relates to 5:6-benzo-.gamma.-pyrone derivatives, to a process for their preparation and to pharmaceutical compositions containing them.
In particular, an object of the present invention is represented by new 5:6-benzo-.gamma.-pyrene derivatives having the following general formula (I)
The present invention provides RANTES mutants with reduced pro-inflammatory activity, increased HIV-suppressive activity, and antagonistic activity to wild-type chemokines.
Chemokines are small proteins involved in inflammatory mechanisms and in physiologic circulation of hemopoietic cells. Several
The present invention provides RANTES mutants with reduced pro-inflammatory activity, increased HIV-suppressive activity, and antagonistic activity to wild-type chemokines.
Chemokines are small proteins involved in inflammatory mechanisms and in physiologic circulation of hemopoietic cells. Several
BACKGROUND OF THE INVENTION
The present invention relates to novel 1,7-fused indole derivatives carrying a substituted piperazinoalkyl radical in the 3-position of the indole ring and salts thereof and to pharmaceutical preparations containing these compounds and to processes and intermediates for
OBJECTS OF THE INVENTION
It is an object of the invention to provide the novel compounds of Formula I and their non-toxic, pharmaceutically acceptable acid addition salts and their preparation.
It is another object of the invention to provide novel anti-allergic and anti-inflammatory compositions
This application is a 371 application of PCT/EP92/00739, filed Apr. 2, 1992.
The invention relates to benzopyranones, whose basic structure may be derived from coumarin, a method for the production of these compounds, including the reactive intermediates then produced, and furthermore medicaments,