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BACKGROUND OF THE INVENTION
A key step in the formation of the nervous system is the determination of proliferating neural progenitor cells to undergo differentiation into neurons and glia. Despite major advances in identification and characterization of neural progenitor cells (Placzek and Furley,
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a national phase application of International Application No. PCT/JP2012/066022, filed Jun. 22, 2012, the content of which is incorporated herein by reference.
TECHNICAL FIELD
The present invention relates to a technique for detecting
This invention pertains to the treatment of human beings suffering from macular degeneration through administration of L-deprenyl or a pharmaceutically acceptable acid addition salt thereof.
BACKGROUND OF THE INVENTION
According to Penfold et al., Senile Macular Degeneration, Investigative
FIELD OF THE INVENTION
This invention discloses the utilization of prosaposin, or fragments thereof, as a cytokine, growth factor or neurotrophin. More specifically, prosaposin may be a neurotrophic factor for populations of neurons for which neurotrophins have yet to be identified.
BACKGROUND OF
TECHNICAL FIELD OF THE INVENTION
This invention is related to the area of eye diseases. In particular, it relates to treating diseases such as glaucoma and macular degeneration
BACKGROUND OF THE INVENTION
A promising strategy for the development of anti-cancer drugs is to suppress activation of
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage application of International Application No. PCT/EP2006/000749, filed on Jan. 28, 2006, which claims priority of German application number 10 2005 005 399.8, filed on Feb. 5, 2005.
BACKGROUND OF THE INVENTION
1. Field of
FIELD OF THE INVENTION
The invention relates generally to methods and compositions for determining whether an individual is at risk of developing age-related macular degeneration by detecting whether the individual has a protective or risk variant of the HTRA1 gene, and to methods and compositions
TECHNICAL FIELD
The present invention relates to the field of clinical care, and in particular to techniques for predicting an onset of cardiorespiratory deterioration in a patient based upon information from physiological sensors.
BACKGROUND ART
Current methods of predicting the onset of
BACKGROUND OF THE INVENTION
Morphological changes occur in the adult vertebrate brain both during normal learning and in various neuropathologies such as epilepsy and Alzheimer's disease (Refs. 1-3). These changes include neurodegeneration and more subtle remodeling of the cellular architecture, and
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a deterioration preventive agent for various milk-containing foods. Namely, the present invention relates to a deterioration preventive agent for milk-containing foods having as its active ingredient a coumarin
TECHNICAL FIELD
The present invention relates to a composition for preventing and treating liver diseases, the composition containing a narirutin extract, which is one of citrus-derived flavonoids, as an active ingredient and a method for extracting narirutin from citrus peel.
BACKGROUND ART
Modern
TECHNICAL FIELD
The present application claims priority from Korean Patent Application No. 10-2015-0072738, filed on May 26, 2015, the entire contents of which are incorporated herein by reference.
The present invention relates to a composition for preventing and treating muscular diseases or
The present invention relates to the use as medicaments of derivatives of cholest-4-en-3-one, in particular as neuroprotectors for example in the pathologies and the traumatisms linked to the degeneration or death of the motor neurons, the pharmaceutical compositions containing them, novel
TECHNICAL FIELD OF THE INVENTION
This invention is related to the area of genetic testing, drug discovery, and Age-Related Macular Degeneration. In particular, it relates to genetic variants which increase the risk of Age-Related Macular Degeneration, particularly in combination with certain
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims the benefit of Japanese Patent Application No. 2018-037556, filed on Mar. 2, 2018 which are hereby incorporated by reference herein in its entirety.
BACKGROUND
Technical Field
The present disclosure relates to an exhaust gas