suma/hypoxia

BACKGROUND OF THE INVENTION (1) Field of the Invention The present invention relates to a novel imidazole derivative, a salt thereof and a medicine comprising the derivative or salt as an active ingredient. More particularly, the present invention relates to a novel N-substituted imidazole

FIELD OF THE INVENTION Modifications to various proteins including, but not limited to, proteins involved in the tricarboxylic acid (TCA) cycle, oxidative phosphorylation (OxPhos) pathways, calcium (Ca.sup.2+) handling, and/or chaperoning, as well as proteins selected from aldehyde dehydrogenase,

BACKGROUND OF THE INVENTION Hypoxia, a state of lower than normal tissue oxygen tension, has recently been implicated in a host of human diseases, including cancer, heart disease, and neurological disorders. An early response to tissue hypoxia is induction of hypoxia inducible factor (HIF), a basic

BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to the field of neuropsychiatry and relates specifically to methods for memory enhancement and treatment of memory deficits consequent to neurological disorders. 2. Description of the Background Art The N-methyl-D-aspartate

The present invention relates to therapeutically-active compounds and their use as well as to pharmaceutical preparations comprising the compounds. The compounds of the invention possess valuable activity as calcium channel blockers which make them useful in the treatment of anoxia, ischemia,

The present invention relates to novel 1,3-disubstituted thiourea compounds and their pharmaceutically acceptable acid addition salts and process for the preparation thereof and composition containing the 1,3-disubstituted thiourea compounds and their salts. More particularly, it relates to

The invention concerns a process for optimizing gene expression in cells. A first aspect concerns a process for changing the expression of a target gene that is present endogenously in a eukaryotic cell by introducing a heterologous expression control sequence or/and an amplification gene into the

BACKGROUND OF THE INVENTION Cardiovascular diseases are a leading cause of death resulting in almost 40% of deaths annually in the United States. Inadequate human myocardial regeneration poses a significant public health problem. It is estimated that 13 million Americans have coronary artery

FIELD OF THE INVENTION The present invention pertains to improved methods for using selegiline in therapeutic applications. In particular, the invention is directed to improved methods for treating certain selegiline-responsive diseases and conditions by administering selegiline either buccally or

BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is directed to methods for increased longevity, delay of aging associated disorders, protection from acute physical stress and induction of regeneration and healing by administration of Long chain Free Fatty Acids (LFFA) and CoA

The present invention relates to therapeutical active compounds and their use as well as to pharmaceutical preparations comprising the compounds. The compounds of the invention possess valuable activity as calcium channel blockers which make them useful in the treatment of anoxia, ischemia,

FIELD OF THE INVENTION The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula ##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically

TECHNICAL FIELD The present disclosure relates to novel crystalline acid salts of a tricyclic derivative or a hydrate thereof, and a production method thereof. BACKGROUND Drugs administered orally show medicinal effects through absorption, distribution, metabolism or elimination, and the intrinsic

BACKGROUND OF THE INVENTION Angiogenesis represents a major challenge in regenerative medicine and tissue engineering. Thus, a need exists for compositions and methods for inducing angiogenesis. SUMMARY OF THE INVENTION The invention relates to the fields which include tissue engineering, advanced

The present invention relate s to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of