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BACKGROUND OF THE INVENTION
Inflammation is the body's defense reaction to injuries such as those caused by mechanical damage, infection or antigenic stimulation. An inflammatory reaction may be expressed pathologically when inflammation is induced by an inappropriate stimulus such as an
BACKGROUND OF THE INVENTION
1. Technical Field of the Invention
This invention relates generally to cytoenzymology, and more particularly to methods and reagents used in cytoenzymology.
2. Discussion of the Background Art
Apoptosis, or programmed cell death, is a process that involves the activation
FIELD OF THE DISCLOSURE
This disclosure relates to the use of Eleutherococcus senticosus maxim extract to inhibit tumor necrosis factor (TNF) in subjects, including humans, animals and cell lines thereof, and to treat disorders mediated by TNF in subjects.
BACKGROUND
It is becoming increasingly
FIELD OF THE INVENTION
The present invention relates to the design and composition of an implant that is used as a growth factor depot to treat avascular necrosis (AVN). More particularly, the depot is in the shape of a small cylinder (straight or curved) or sphere that can be delivered into
FIELD OF THE INVENTION
The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and
FIELD OF THE INVENTION
The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
REFERENCE TO RELATED APPLICATIONS
Related applications U.S. Ser. No. 13/131,231, .sctn.371(c) Date Feb. 2, 2012, PCT/US2009/065755, filed Nov. 24, 2009, and U.S. 61/117,917, filed Nov. 25, 2008 are herein incorporated by reference in their entireties.
REFERENCE TO SEQUENCE LISTING SUBMITTED
REFERENCE TO A SEQUENCE LISTING SUBMITTED ELECTRONICALLY VIA EFS-WEB
The content of the electronically submitted sequence listing (Name: sequencelisting.ascii.txt, Size: 115,276 bytes; and Date of Creation: May 25, 2011) is herein incorporated by reference in its entirety.
BACKGROUND OF THE
FIELD OF THE INVENTION
The present invention relates to a surgical adjuvant composition that provides for reduced tissue and cellular necrosis and/or apoptosis. The composition is particularly useful, for example, for use in arthroscopic surgical procedures and other minimally invasive endoscopic
FIELD OF THE INVENTION
The present invention relates to a surgical adjuvant composition that provides for reduced tissue and cellular necrosis and/or apoptosis. The composition is particularly useful, for example, for use in arthroscopic surgical procedures and other minimally invasive endoscopic
BACKGROUND OF THE INVENTION
The present invention relates to the treatment of cancer with a parenteral nutritional supplement, particularly a supplement having a specific class of structured lipids as its primary fat source. Surprisingly, the supplement containing these structured lipids, when used
BACKGROUND OF THE INVENTION
Compounds which have the property of inhibiting the action of metalloproteinases involved in connective tissue breakdown such as collagenase, stromelysin and gelatinase (known as "matrix metalloproteinases", and herein referred to as MMPs) are thought to be potentially