swietenine/swietenia

The ether extract from the seeds of Swietenia mahagoni Jacq. (Meliaceae) was found to inhibit platelet-activating factor (PAF)-induced platelet aggregation. Systematic separation of the extract afforded twenty eight tetranortriterpenoids related to swietenine and swietenolide. Among them, several

As a traditional plant medicine in tropical areas, Swietenia macrophylla seeds are usually applied for some chronic diseases, including hypertension, diabetes, and so on. Few studies have been carried out to identify the effective elements in seed extract and their indications. In this study, we

Swietenine, a tetranortriterpenoid, was isolated from the Swietenia macrophylla seeds. The in vivo hypoglycemic activity was evaluated against neonatal-streptozotocin induced type 2 diabetic rats. Oral administration of swietenine at 25 and 50 mg/kg body weight per day to diabetic rats was found to

The present study was undertaken to isolate a novel antidiabetic molecule from Swietenia macrophylla seeds. The hydroalcohol extract of Swietenia macrophylla seeds was subjected for bioassay guided isolation employing glucose utilization assay by the isolated rat hemi-diaphragm method in vitro. One

A new limonoid, swietemacrophin (1), was isolated from the seeds of Swietenia macrophylla, together with five known compounds 2-6. The structure of 1 was determined through extensive 1D/2D-NMR and mass-spectrometric analyses. Swietemacrophin (1), humilinolide F (2), 3,6-O,O-diacetylswietenolide (3),

One new limonoid of the phragmalin type (1) named Swietenine J with nine known compounds methyl-6-β-hydroxy angolensate (2), 1-O-acetylkhayanolide A(3), Khayanolide E (4), Khayalactone (5), Khayanone (6), 1-O-Acetylkhayanolide B (7), 1-O-Deacetylkhayanolide E (8), Khayanolide A (9), Khayanolide B

To study the chemical constituents from the fruit of Swietenia macrophylla. The chemical constituents were extracted and isolated by silica gel, Sephadex LH-20. The chemical structures of components were further elucidated by the physicochemical characters and MS,NMR spectral data. 17 compounds were

Natural resources provide more efficient and safer alternatives in managing diabetes compare to the synthetic oral anti diabetes (OAD). The plants not only have hypoglycemic effect, but also prevent its complications; in which no synthetic drugs provide of both