tetrahydrocolumbamine/corydalis

OBJECTIVE To study the alkaloid constituents of Corydalis adunca. METHODS The constituents were isolated on silica gel column and their structures were elucidated by IR, NMR, MS data. RESULTS Eight alkaloid compounds were isolated from alcohol extracts of the herb of C. adunca, and identified as

Monoamine oxidase-A (MAO-A) is considered an important therapeutic target in depression. In order to rapidly screen and identify novel MAO-A inhibitors from natural products, a magnetic bead (MB) based drug discovery tool was developed in this study. MAO-A was first immobilized onto the surface of

OBJECTIVE To study the chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo. METHODS Compounds were isolated and purified by a macroporous resin, Sephadex LH-20, ODS column chromatography, and prepared TLC. Their structures were identified by spectral

Corydalis Rhizoma is the dried tuber of Corydalis yanhusuo W.T. Wang which is used in traditional Chinese medicine for pain relief and blood activation. Before being used in the clinics, C. yanhusuo is traditionally processed through dry-frying or frying with vinegar, wine or salt. In this study,

The tuber of Corydalis yanhusuo is a famous traditional Chinese medicine and found to have potent pharmacological effects, such as antinociceptive, antitumor, antibacterial, anti-inflammatory, and anti-depressive activities. Although there are several methods to be developed for the analysis and

OBJECTIVE To investigate the chemical constituents of Corydalis yanhusuo. METHODS The compounds were isolated and purified by column chromatography over macroporous absorption resin, silica gel, and Sephadex LH-20. Their structures were elucidated on the basis of physicochemical properties and