3 结果
OBJECTIVE
To isolate and characterize compounds from the stems of Schisandra propinqua.
METHODS
Extracting with solvent, isolating by column chromatography and identifying by the spectroscopic methods.
RESULTS
Six dibenzocyclooctadiene lignans were isolated and identified as tigloylgomisin P(1),
BACKGROUND
The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited.
OBJECTIVE
Elucidation of the cytotoxic constituents
Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4),