7 结果
From the stem bark of Strychnos malacoclados, one new bisindole alkaloid, 3-hydroxylongicaudatine Y (1), was isolated along with the known alkaloids vomicine (2), bisnordihydrotoxiferine (3), divarine (4), longicaudatine (5), longicaudatine Y (6), and longicaudatine F (7). All the compounds were
The contents of four alkaloids in different processed products of Strychnos nux-vomica hamely, vomicine, icajine, strychnine N-oxide and brucine N-oxide, were determined by TLC-densitometry. The relationship between alkaloid contents and processing methods was studied.
Thirteen alkaloids were isolated from the seeds of Strychnos nux-vomica. They were identified as strychnine, beta-colubrine, pseudostrychnine, strychnine N-oxide, brucime, brucine N-oxide, novacine, icajine, vomicine, isostrychnine, isobrucine, isobrucine N-oxide and isostrychnine N-oxide by
To isolate and identify the chemical constituents from the seeds of Strychnos nux-vomica.
Chromatographic separation techniques such as silica gel chromatography,ODS chromatography and Sephadex LH-20 chromatography were used for the isolation and purification. The structures of the chemical
Results of experiments showed that the contents of strychnine and brucine were about the same in decoction of Strychnos nux-vomica and S. pierriana, but the contents of vomicine, strychnine N-oxide and brucine N-oxide were greater in the former than in the latter. The contents of strychnine and
Reinvestigation of Strychnos icaja Baillon resulted in the isolation of vomicine, isostrychnine and of three new sungucine derivatives, named isosungucine (8), 18-hydroxy-sungucine (9) and 18-hydroxy-isosungucine (10). They were identified by detailed spectroscopic methods. The complete 1H- and
BACKGROUND
Strychnos nux-vomica, commonly known as kuchla, contains strychnine and brucine as main constituents. Minor alkaloids present in the seeds are protostrychnine, vomicine, n-oxystrychnine, pseudostrychnine, isostrychnine, chlorogenic acid, and a glycoside. Seeds are used traditionally to