white/atrophy

BACKGROUND Livedoid vasculitis is a clinico-pathological entity which may be idiopathic or secondary to various disorders. The aim of this study was to search for a thrombogenic biological abnormality in patients with apparently idiopathic livedoid vasculitis. METHODS All the patients with

There are two clinical phenomena which, owing to the French School, are still subject to violent criticism: the phenomenon described by M. Raynaud (1862) and the white atrophy termed Milian's (1929). Perhaps badly defined by the authors, the facts have been reviewed, but microcirculation - that of

The author was, in 1952, the first to draw attention to the possibilities of revascularization of white atrophy. The data which he produced in 1952 have remained correct. Time has amply confirmed them and so, using these data, the author studies the nature of revascularization; he underlines the

OBJECTIVE Although age-related brain changes are becoming better understood, midlife patterns of change are still in need of characterization, and longitudinal studies are lacking. The aim of this study was to determine if baseline fractional anisotropy (FA), obtained from diffusion tensor imaging

White atrophy, defined by Milian, is a smooth ivory white plaque, slightly depressed, of variable dimensions, and surrounded by a pigmented telangiectasic area, several millimetres across. It is usually localised in the lower limbs and mostly affects middle-aged women. It is a symptom with multiple

The importance of macrostructural white matter changes, including white matter lesions and atrophy, in intact brain functioning is increasingly being recognized. Diffusion tensor imaging (DTI) enables measurement of the microstructural integrity of white matter. Loss of white matter integrity in

We report two brothers who suffer from infantile onset optic atrophy and blindness. MRI of the brain demonstrated periventricular white matter changes in both children. Neurological and developmental examination are normal. Extensive laboratory investigations rule out metabolic disorders that can be