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Roth spots (white-centred retinal haemorrhages) were classically described as septic emboli lodged in the retina of patients with subacute bacterial endocarditis. Indeed many have considered Roth spots pathognomonic for this condition. More recent histological evidence suggests, however, that they
White-centered hemorrhages which are seen rather seldom nowadays are traditionally associated with serious diseases (i.e. septicemia or leukemia). We describe a case of benign infectious mononucleosis with several white-centered hemorrhages.
Acute leukemias are a heterogeneous group of hematological malignancies (blood cancers) that are rapidly life-threatening in the absence of treatment. They constitute a diagnostic and therapeutic emergency. Ocular manifestations are more frequent but less revealing of the disease, most The use of laboratory testing can be very helpful in the differential diagnosis of ocular disease. White-centered hemorrhages are associated with many systemic diseases. This paper discusses how the differential diagnosis of the associated medical condition can be accomplished through a systematic
Two hundred fifteen diabetic patients (430 eyes) with early proliferative retinopathy, moderate-to-severe nonproliferative retinopathy, and/or diabetic macular edema in each eye were examined for the presence of white centered retinal hemorrhages (WCRHs). Of the eyes examined, 15.6% demonstrated at
The white nipple sign is a term used to describe a fresh fibrin clot on a varix that has bled recently. The authors describe a case to highlight the importance of prompt endo-therapy when this sign is recognised as disturbing this clot can cause brisk bleeding.
To see if the systemic inflammation profile of 123 infants born before the 28th week of gestation who had intraventricular hemorrhage without white matter injury differed from that of 68 peers who had both lesions, we compared both groups to 677 peers who had neither. Cranial ultrasound scans were
Retinal involvement during leukemia is frequent (varying from 28% to 50%), can be the result of different mechanisms, and may reveal the disease. We describe two patients, 10 and 50 years old, who consulted for a sudden drop in visual acuity. Fundus examination showed bilateral retinal hemorrhage
Epizootic hemorrhagic disease affects wild and domestic ruminants and has recently spread northward within the United States. In September 2017, we detected epizootic hemorrhagic disease virus in wild white-tailed deer, Odocoileus virginianus, in east-central Canada. Culicoides spp. midges of the