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FIELD OF THE INVENTION
The present invention relates to genetically engineered subtilisin proteases which are useful in compositions such as, for example, personal care compositions, laundry compositions, hard surface cleansing compositions, and light duty cleaning compositions.
BACKGROUND OF THE
FIELD OF THE INVENTION
The present invention relates to serine protease variants and compositions comprising the variants which have decreased immunogenicity relative to their corresponding wild-type serine proteases.
BACKGROUND OF THE INVENTION
Enzymes make up the largest class of naturally
FIELD OF THE INVENTION
The present invention relates to serine protease variants and compositions comprising the variants which have decreased immunogenicity relative to their corresponding wild-type serine proteases.
BACKGROUND OF THE INVENTION
Enzymes make up the largest class of naturally
FIELD OF THE INVENTION
It is well-known in the field of drug development that the pathogenicity of various microorganisms, such as viruses, bacteria and the like, may be eliminated, or at least controlled, by inactivating certain proteins essential to the survival and/or proliferation of the
FIELD OF THE INVENTION
The present invention relates to compounds useful for inhibiting HIV protease enzymes. More particularly, the present invention relates to HIV protease inhibitors, methods of manufacturing the inhibitors, and their use as therapeutic agents, for example, in treating wild-type
FIELD OF THE INVENTION
The present invention relates to compounds useful for inhibiting HIV protease enzymes. More particularly, the present invention relates to HIV protease inhibitors, methods of manufacturing the inhibitors, and their use as therapeutic agents, for example, in treating wild-type
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention concerns amino acid sequence variants of hepatocyte growth factor (HGF), methods and means for preparing such variants, and pharmaceutical compositions comprising them.
II. Description of Background and Related Art
HGF was
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention concerns amino acid sequence variants of hepatocyte growth factor (HGF), methods and means for preparing such variants, and pharmaceutical compositions comprising them.
II. Description of Background and Related Art
HGF was
BACKGROUND OF THE INVENTION
The process of angiogenesis is central to the pathology of conditions including malignancy, diabetic retinopathy and macular degeneration. That cancer is angiogenesis-dependent has been recently supported by experimentation in which striking inhibition of tumor growth can
BACKGROUND OF THE INVENTION
The process of angiogenesis is central to the pathology of conditions including malignancy, diabetic retinopathy and macular degeneration. That cancer is angiogenesis-dependent has been recently supported by experimentation in which striking inhibition of tumor growth can
BACKGROUND OF THE INVENTION
The process of angiogenesis is central to the pathology of conditions including malignancy, diabetic retinopathy and macular degeneration. That cancer is angiogenesis-dependent has been recently supported by experimentation in which striking inhibition of tumor growth can
TECHNICAL FIELD
This invention relates to novel mutant protease enzymes or enzyme variants useful in formulating detergent compositions and exhibiting increased autoproteolytic stability; cleaning and detergent compositions containing said enzymes; mutated genes coding for the expression of said
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority of Danish application Ser. Nos. 1235/96, 1240196 and 0284/97 filed on Nov. 4, 1996, Nov. 5, 1996 and Mar. 14, 1997, respectively, the contents of which are fully incorporated herein by reference.
TECHNICAL FIELD
This invention
SUBMISSION ON COMPACT DISC
The contents of the following submission on compact discs is incorporated herein by reference in its entirety: two copies of the Sequence Listing (COPY 1 and COPY 2) and a computer readable form copy of the Sequence Listing (CRF COPY), all on compact disc, each containing:
BACKGROUND OF THE INVENTION
1. Technical Field
The present invention relates to novel proteolytic enzymes having improved properties for use in detergents. These properties include improved stain removing ability in laundry detergent washing compositions, improved stability in laundry detergents