4 结果
INTRODUCTION
1. Field of the Invention
The field of the invention is inducing, detecting and modulating nervous system seizure in animal systems.
2. Background of the Invention
Human seizure disorders are a substantial health problem because of the large number of affected individuals and the
BACKGROUND
Epilepsy is a neurological disorder defined by recurrent spontaneous seizures. Approximately 1% of people in the US have epilepsy. Seizures are associated with cell toxicity, hyperexcitability and death. Anti-epileptic drugs act primarily on ion channels and receptors for calcium, sodium,
INTRODUCTION
Technical Field
The invention relates to transgenic animals with progressive neurologic disease characterized by both behavioral and neuropathological changes as compared to nontransgenic age-matched animals and their use for screening for agents which can be used to treat or cure
INTRODUCTION
1. Technical Field
The invention relates to transgenic animals with progressive neurologic disease characterized by both behavioral and neuropathological changes as compared to nontransgenic age-matched animals and their use for screening for agents which can be used to treat or cure