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Scleral Hydrops and Intralabyrinthine Schwannoma

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狀態
贊助商
University Hospital, Strasbourg, France

關鍵詞

抽象

The symptoms of intralabyrinthine schwannomas (vertigo, deafness, instability, tinnitus) cut across the symptoms found in pressure pathologies involving the inner ear, particularly the endolymphatic hydrops.
Some publications have described dilatation of the membranous labyrinth (hydrops) in the presence of intralabyrinthine tumors.
It would be interesting to measure the size of the saccule (structure of the membranous labyrinth) in the presence of an intralabyrinthine schwannoma, to evaluate if some of the symptoms presented by the patients could be explained by the concomitant presence of an endolymphatic hydrops (accessible to drug therapy - Betahistine).

日期

最後驗證: 05/31/2018
首次提交: 06/25/2018
提交的預估入學人數: 06/25/2018
首次發布: 07/09/2018
上次提交的更新: 06/25/2018
最近更新發布: 07/09/2018
實際學習開始日期: 06/21/2018
預計主要完成日期: 05/31/2019
預計完成日期: 05/31/2019

狀況或疾病

Hydrops Saccular

-

資格標準

有資格學習的年齡 18 Years 至 18 Years
有資格學習的性別All
取樣方式Non-Probability Sample
接受健康志願者
標準

Inclusion Criteria

- Age> 18,

- Subject having benefited from an exploration of internal auditory canals by MRI in our service at CHU de Hautepierre between January 1, 2008 and October 1, 2017

- Presence on the MRI of the internal auditory ducts, including the realization of a high resolution fluid sequence of FIESTA-C (exploitable) type, of an intralabyrinthine schwannoma, without extension to the internal auditory canal.

- Subject who has agreed to the use of medical data for the purposes of this research.

Criteria for Non Inclusion

- Refusal of the patient to participate in the study

- Absence of high resolution fluid sequence of fast imaging employing steady state acquisition (FIESTA-C)

- Presence of movement artifacts interfering with the interpretation of the FIESTA-C sequence

- Interior surgery of the inner ear or pontocerebellar angle, without preoperative imaging Inflammatory or infectious pathology of the concomitant middle or inner ear

- Extension of schwannoma to the internal auditory canal

- Impossibility of giving the subject informed information (difficulty understanding the subject,)

- Subject under the protection of justice

- Subject under guardianship or curatorship

結果

主要結果指標

1. Size of intralabyrinth saccules [1 hour after the realization of the MRI]]

To measure saccule size (membranous labyrinth structure) in patients with intralabyrinthine schwannoma on a high resolution fluid sequence (FIESTA-C) in 3T MRI

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