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BMC Neurology 2014-Jul

Positivity to p-ANCA in patients with status epilepticus.

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Edoardo Ferlazzo
Antonio Gambardella
Marina Bellavia
Sara Gasparini
Laura Mumoli
Angelo Labate
Vittoria Cianci
Concetta Russo
Umberto Aguglia

關鍵詞

抽象

BACKGROUND

Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different autoimmune disorders but are particularly associated with systemic vasculitis named ANCA-associated-vasculities (AAV). We herein report 3 patients with SE and positivity to p-ANCA.

METHODS

One patient had a catastrophic evolution and died 5 months after disease onset. The other two patients had a good outcome and remained seizure-free at 30 months and 5 years of follow-up respectively.

CONCLUSIONS

This report highlights the importance of considering ANCA dosage in patients with SE of unclear origin.

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