berberis amurensis/infarction

BACKGROUND Berberine, an isoquinoline alkaloid isolated from the Berberis aristata, has been shown to display a wide array of pharmacological activities (hypoglycaemic and hypolipidemic). OBJECTIVE The present study was designed to investigate whether these pharmacological properties translate into

Berbamine (BBM), a bisbenzylisoquinoline alkaloid from roots, bark, and stem of Berberis plant such as Berberis aristata has a wide range of pharmacological activities. However, the evidence for the cardioprotective effect of BBM is inadequate and the molecular mechanism of BBM remains unclear. This

BACKGROUND Berbamine, a natural compound from Barberry, was reported to protect myocardium from ischemia/reperfusion (I/R) injury, but the underlying mechanisms are largely unknown. RESULTS Berbamine pretreatment from 10 to 100nmol/L concentration-dependently improved post-ischemic myocardial