black/抗抑鬱藥

In 2004 the Food and Drug Administration (FDA) required a black-box warning on antidepressants that describes a possible suicide risk in children. An analysis of the events, evidence, and FDA actions reveals information asymmetries that affect various players' ability to identify and act on risks.

OBJECTIVE The purpose of this review is to assess whether evidence supports a favorable risk/benefit profile for pediatric antidepressant use and reconsideration of the black box. METHODS The review examines studies post-black box purporting to show declines in pediatric antidepressant use and

OBJECTIVE The purpose of this pilot study was to identify ethnic group differences in nonadherence and to determine predictors of nonadherence to antidepressant medications in older minority-group members. METHODS Participants were 49 black and 52 Latino subjects over the age of 55 who had been

CRY2 genetic variants associate with the depressive episodes in a range of mood disorders. Expression of core clock genes is highly responsive to stimuli in brown fat. Brown fat clocks might synchronize clocks in other tissues through their control of heat production and core body temperature. Among

OBJECTIVE The study objective was to estimate the prevalence and correlates of antidepressant use by black and white Americans. METHODS Data from the Collaborative Psychiatric Epidemiology Surveys (CPES) were analyzed to calculate nationally representative estimates of past-year antidepressant use