canavanine/sarcoma

Previous studies have established that glucose deprivation of murine cells suppresses the synthesis of an Mr = 85,000 polypeptide. A protein of approximately the same molecular weight has been found to be associated with the transforming protein of Rous sarcoma virus, pp60src. The present study

L-Canavanine (L-CAV) is a naturally occurring L-arginine analog that induces the formation of non-functional proteins in a variety of organisms. Previous studies have shown that L-CAV is cytotoxic for several human tumor cell lines. In this study, we have evaluated the cytotoxicity of L-CAV for both

The viral proteins of Moloney murine sarcoma virus-transformed mouse cells (G8-124), that overproduce the sarcoma virus relative to helper leukemia virus, were examined by immunoprecipitation, sizing by gel electrophoresis and peptide mapping. Using antisera to the viral core proteins, a

Canavanine is an arginine analog which is widely used to inhibit proteolytic processing of viral polyproteins. Certain results obtained with canavanine have suggested that it may have other effects. Therefore, we examined the effects of canavanine on the cell-free synthesis of murine retrovirus

The purpose of this work was to collect the main information from the literature about the biotyping of Cryptococcus neoformans. The more up-to date research concerning the epidemiology of cryptococcosis comprising quite a few articles, mainly after the advent of AIDS, was also reviewed. The

Several amino acid analogs were tested for their ability to induce type C virus from a cloned Balb/c mouse cell line transformed by Kirsten sarcoma virus. O-Methylthreonine and hydroxynorvaline, analogs of isoleucine and threonine, respectively, were found to induce type C virus with the host range