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carotenoid/hypoxia

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As a result of the examination of 76 patients with atherosclerosis (57 with ischemic stroke and 19 with chronic cerebrovascular insufficiency) the authors have established a definite correlation between the blood levels of carotinoids and the degree of hypoxia and cerebral ischemia, as well as

The carotenoid crocetin enhances pulmonary oxygenation.

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Rabbits anesthesized with urethan and subjected to mild hypoxia (60-70 Torr arterial PO2) through a reduction of the minute volume were injected with a carotenoid compound, crocetin, or saline. The increased PO2 in the arterial blood seen subsequently with crocetin is attributed to increased
Background: The pathogenesis of chronic obstructive pulmonary disease (COPD) is associated with oxidative stress. Both iron (Fe) and oxygen are involved in the chemical reactions that lead to increased formation of reactive oxygen species. Oxidative reactions are prevented by antioxidants such as
Hypoxia as one of the most common clinical disturbances in pregnancy period can cause destructive changes in motor sensory cortex and can lead to imperfect organization in motor reactions. Crocin, a water-soluble carotenoid, is the most active ingredients of saffron and a lot of studies declare its
We examined the decay of chlorophyll a and the carotenoid fucoxanthin in oxic and anoxic sediment microcosms, with and without the deposit-feeding benthic amphipod Monoporeia affinis, over 57 days at 5 degrees C. Deep frozen phytoplankton from the Baltic Sea proper was added to all but a few

Intravenous crocetinate prolongs survival in a rat model of lethal hypoxemia.

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OBJECTIVE To examine whether a carotenoid, trans-sodium crocetinate, has beneficial effects on hemodynamic status and short-term outcome in a rat model of lethal hypoxemia. METHODS Randomized, placebo-controlled study. METHODS Medical school laboratory. METHODS Eighteen spontaneously breathing,
METHODS Our aim was to investigate whether dietary wolfberry altered carotenoid metabolic gene expression and enhanced mitochondrial biogenesis in the retina of diabetic mice. RESULTS Six-week-old male db/db and wild-type mice were fed the control or wolfberry diets for 8 weeks. At study

Lutein protects RGC-5 cells against hypoxia and oxidative stress.

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Retinal ischemia and oxidative stress lead to neuronal death in many ocular pathologies. Recently, we found that lutein, an oxy-carotenoid, protected the inner retina from ischemia/reperfusion injury. However, it is uncertain whether lutein directly protects retinal ganglion cells (RGCs). Here, an
Retinal pigment epithelial (RPE) cells are central to retinal health and homoeostasis. Oxidative stress-induced damage to the RPE occurs as part of the pathogenesis of age-related macular degeneration and neovascular retinopathies (e.g., retinopathy of prematurity, diabetic retinopathy). The
BACKGROUND Hypoxia/reoxygenation(H/R)-induced apoptosis of cardiomyocytes plays an important role in myocardial injury. Lycopene is a potent antioxidant carotenoid that has been shown to have protective properties on cardiovascular system. The aim of the present study is to investigate the potential
The lumped parameter describing skeletal muscle diffusional conductance for O(2), DM(O(2)), reflects all of the resistances for O(2) in moving from red cell to muscle fiber mitochondria. The purpose of our study was to determine if the carotenoid compound, trans sodium crocetinate (TSC), which has
Compositions and contents of sedimentary pigments were examined using high performance liquid chromatography in order to discuss the spatial distributions of phytoplankton primary production, phytoplankton functional type and the preservation efficiency of phytoplankton pigments and their
Deep-sea sediments of the eastern Mediterranean harbour a series of dark, organic carbon-rich layers, so-called sapropels. Within these layers, the carotenoid isorenieratene was detected. Since it is specific for the obligately anaerobic phototrophic green sulfur bacteria, the presence of
Pigments determined by high performance liquid chromatography (HPLC) provide useful information concerning water column and epibenthic plant and microbial communities in both extant communities and accumulated sediments in lakes, estuaries and the ocean. Chlorophyll and its degradation products
Limited evidence up to now indicates low linear photosynthetic electron flow and CO(2) assimilation rates in non-foliar chloroplasts. In this investigation, we used chlorophyll fluorescence techniques to locate possible limiting steps in photosystem function in exposed, non-stressed green fruits
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