carvone/hypersensitivity

Carvone has occasionally been reported as an allergen, usually in flavorings. Isomers of carvone have been either a mint or a rye flavor and aroma. We report a woman with positive patch-test reactions to carvone (newly added to the North American Contact Dermatitis Group standard series) and

We have previously reported a reduction of sensitization to carvone in guinea pigs when adding non-allergenic, structurally related compounds simultaneously at induction. This study investigates the criteria needed to obtain a reduction of sensitization in contact allergy. Linalool, a non-sensitizer

In the present study, the mechanism for the antigen formation of alpha, beta-unsaturated ketones was investigated. A series of analogues of carvone ((5R)-5-isopropenyl-2-methyl-2-cyclohexenone) with altered chemical reactivity and with retained overall structure or with retained reactivity and

BACKGROUND Toothpastes have widespread use in the population, and contain flavours to give a pleasant and often minty aroma. Flavours are prevalent allergens in toothpastes, and adverse reactions often present as perioral dermatitis or stomatitis. l-Carvone, a mint flavour found in spearmint oil, is

Consumer and medical products can contain leachable chemical allergens which can cause skin sensitization. Recent efforts have been directed at the development of non-animal based tests such as in vitro cell activation assays for the identification of skin sensitizers. Prohapten identification by in

R-(+)-Limonene is an ubiquitous allergen in our environment. It is one of the most widely used fragrance materials not only in fine fragrances but also most often incorporated in domestic and occupational products. Although the non-oxidized R-(+)-limonene itself is not allergenic, it easily forms

BACKGROUND Dental restorative materials containing silver-mercury compounds have been known to induce oral lichenoid lesions. OBJECTIVE To determine the frequency of contact allergy to dental restoration materials in patients with oral lichenoid lesions and to study the effect of removal of the

Data on the chemistry of essential oils which have caused contact allergy are provided. The largest group of chemicals found in essential oils consists of terpenes. The number of identified components usually ranges from 100 to 250, but in some oils (lavender, geranium, rosemary) 450 to 500

BACKGROUND Melaleuca oil (tea tree oil) is the essential oil distilled from the leaves of Melaleuca alternifolia Cheel. Tea tree oil is popular for treating various cutaneous maladies. OBJECTIVE Our purpose was to determine which constituent compounds of Melaleuca oil are responsible for allergic