4 結果
TECHNICAL FIELD OF THE INVENTION
The invention relates to a diagnostic assay for determining susceptibility to breast cancer based on the sequence of the 3' untranslated region of the prohibitin gene.
BACKGROUND OF THE INVENTION
Breast cancer is the second leading cause of cancer-related deaths of
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims the benefit of priority to the following applications: International application number PCT/EP2003/010881, filed 1 Oct. 2003 and published as WO 2004/035803; German application number 10245779.4, filed 1 Oct. 2002; German application
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a United States nationalization, under 35 U.S.C. .sctn.371, of PCT/EP04/014170, filed 13 Dec. 2004, and additionally claims the benefit of priority to European applications: EP 03090432.0, filed 11 Dec. 2003; EP 04090041.7, filed 10 Feb.
FIELD OF THE INVENTION
Compositions and methods for inhibiting the activity of specific genes are provided and in particular, modified oligodeoxyribonucleotides and methods of using same are provided which prevent transcription of certain gene sequences.
BACKGROUND OF THE INVENTION
Oncogenes have