diosgenin/solanum

Bioassay-directed fractionation of the cytotoxicity active fraction of the whole plant from Solanum lyratum led to the isolation of a new steroidal saponin, diosgenin 3-O-beta-D-glucopyranosiduronic acid methyl ester (2), as well as four known compounds, diosgenin (1), diosgenin

Diosgenin and beta-sitosterol were isolated from Solanum xanthocarpum callus, crystallized, and chemically characterized. That these metabolites, particularly diosgenin, form in significant amounts in tissue culture may prove useful.

This report presents evidence that the following Solanum steroids: solasodine, diosgenin and solanine interact with human erythrocytes and molecular models of their membranes as follows: a) X-ray diffraction studies showed that the compounds at low molar ratios (0.1-10.0mol%) induced increasing

Callus and cell suspension cultures were established with shoots of the soladulcidine variety of the bittersweet Solanum dulcamara L. Plantlets were regenerated from undifferentiated callus. From mixotrophic callus as well as mixotrophic suspension cultures soladulicidine, solasodine and the

In seeds of Solanum dulcamara L. the 4,4-dimethylsterols cycloartenol, lanosterol, cycloartanol, 24-dihydrolanosterol, 24-methylenecycloartanol, and 24-methylenelanost-8-en-3beta-ol, the 4alpha-methylsterols 31-norcycloartenol, 31-norlanosterol, 31-norlanost-8-en-3beta-ol, lophenol, cycloeucalenol,

Solanum nigrum L., commonly known as black nightshade, is used worldwide for the treatment of skin and mucosal ulcers, liver cirrhosis and edema. We aimed to determine the anti-inflammatory active fraction of S. nigrum by serial extractions. S. nigrum was first extracted with methanol, then

Steroidal saponins are widely distributed in many plant species. Their diverse structures have resulted in a wide range of applications, including drug and medicine production. It has been suggested that the nature of the non-saccharide and oligosaccharide portions of the saponin molecule both

In addition to solamargine and proto-dioscin, three new steroid glycosides, abutilosides A-C, have been isolated from roots of the Solanaceae Solanum abutiloides. The structure of abutiloside A has been elucidated as 3 beta, 16 alpha-dihydroxy-26-isovalerylamino-5 alpha,25 xi H-cholestan-22-one

Various in vitro grown tissues (non-regenerative callus, regenerative callus and microshoot derived leaves) of Solanum nigrum L. were cultured under salinity stress (0-150 mM NaCl) for enhanced production of solasodine, a steroidal alkaloid and an alternative to diosgenin, which is used as a

OBJECTIVE To study the chemical constituents of Solanum lyratum, And to explore the anti-tumor effect of some steroidal compounds from it. METHODS The chemical constituents were isolated and purified via silica gel and Sephadex LH-20 column chromatography as well as recrystallization. Their