diterpene lactone/tripterygium

The male antifertility activities under equal toxic dosages 1/10-1/60 LD50 and hemolysin antibody formation parameters under effective threshold dosages respectively of 7 diterpene lactone epoxide compounds extracted from Tripterygium wilfordii (TW) were assayed in mice. The results indicated that

The half-effective dose(ED50), therapeutic index(TI) and certain safety factor(CSF) of 7 diterpene lactone epoxide compounds with antiinflammatory and immunosuppressive action extracted from Tripterygium wilfordii (TW) were assayed using croton oil-induced ear swelling and hemolysin-antibody

The inhibitory effects and their IC50 values of Tripterygium wilfordii (TW) on T and B lymphocytes were assayed using mice splenocytes induced to proliferate by mitogens ConA and LPS in vitro. The results indicated that 6 compounds (T4,T7,T8,T9,T10,L2) and component T1 had significant inhibitory

In suspension culturing of Tripterygium wilfordii, 18.4 mg/l of dry cells and 9.184 mg/l of diterpene-lactone compounds were obtained from 6,7-V liquid medium containing 1 mg/l NAA. Besides those within the cells, diterpene-lactone compounds were also found in the cultured liquid and the yield

A new kaurane type diterpene lactone, neotripterifordin (1), has been isolated from the roots of Tripterygium wilfordii. The structure of 1 was elucidated by spectroscopic methods, which included the concerted application of a number of 2-D NMR techniques including 1H-1H COSY, phase-sensitive NOESY,

A new kaurane-type diterpene lactone, tripterifordin [1], has been isolated from the roots of Tripterygium wilfordii. The structure of 1 was elucidated by spectroscopic methods, including the concerted application of a number of 2D nmr techniques that involved the 1H-1H COSY, heteronucleus-detected