encephalartos lebomboensis/neoplasms

The South African Encephalartos species which are known or have been shown experimentally to be toxic and/or carcinogenic are reviewed briefly. The kernel of E. lanatus, the toxic and carcinogenic principle of which is macrozamin, is a potent hepatotoxin and carcinogen when fed to rats. Renal

Cycads, the most primitive of the living gymnosperms, have been used and continue to be used for food and medicinal purposes by many cultures, although toxins must be removed before ingestion. In our quest to identify tropical plants that contain inhibitors of the cytochrome P-450 aromatase and thus