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Previous studies reported that the expression of miR-23b-27b cluster was downregulated in embryonic brain cortices during hypoxia-induced neuronal apoptosis. However, the mechanism underlying this downregulation is not completely understood. Here, we report that the transcription factor c-Myc plays
The present chapter presents the experience of the author during his fellowship granted by the Fogarty Foundation of the NIH in the Division of Perinatal Biology, Loma Linda University, from 1989 to 1991. Experiments on maternal and fetal responses to long-term hypoxemia (including high-altitude)
To introduce approximate entropy (ApEn) in the analysis of fetal heart rate variability (FHRV) and to discuss the relationship between the ApEn values and perinatal outcomes, 67 computerized cardiotocographs were recorded. Approximate entropy and index in time domain were used to analyze FHRV. After
OBJECTIVE
To examine the effectiveness of pH analysis of fetal scalp blood compared with lactate analysis in identifying hypoxia in labour to prevent acidaemia at birth.
METHODS
Randomised controlled multicentre trial.
METHODS
Labour wards.
METHODS
Women with a singleton pregnancy, cephalic
Use of cardiotocography as the fetal status index in complex with other criteria and medical algorithms in pregnant women during the IIIrd trimester helped better select the term and method of delivery for each patient with threatened fetal distress. The choice of the optimal individual method of
A study was done from May 1995 to February 1996 to evaluate the justification of caesareans for fetal distress by examining the circumstances leading to operative delivery for compromised fetus. Of the 1096 caesareans, 179 (16.33%) were for fetal distress. One hundred and seven (59.78%) were
Blood gas and acid-base assessment of maternal dorsalis pedis artery and umbilical artery and vein was carried out immediately after delivery in 46 cases of normal term pregnancy and 41 cases of pregnancy with fetal distress (FD). Blood gas and acid-base equilibrium differences between vaginal
Animal and human studies suggest that fetal oliguria is a normal physiologic response to hypoxemia. To assess the clinical significance of this observation, we studied (before their admission) 51 fetuses of women whose pregnancies were complicated by oligohydramnios at greater than or equal to 38
The measurement of fetal blood flow velocity and 24 h monitoring of fetal heart-rate (FHR) using a computer were performed to clarify the haemodynamics of growth-retarded fetuses with chronic hypoxia. One hundred normal-growth and 18 growth-retarded fetuses were analysed. All the growth-retarded
OBJECTIVE
To evaluate and compare third trimester ultrasound measurements of fetal size and growth velocity in the prediction of intrapartum operative delivery for fetal distress and admission to the special care baby unit in a low risk antenatal population undergoing labour at
Although effects of stress on the stomach have been extensively investigated in children and adults, our knowledge about effects of fetal distress (FD) on the fetal stomach is quite limited. Therefore, an experimental study was planned to evaluate the effects of FD on fetal gastric physiology and
OBJECTIVE
To explore possible spinal cord dysfunction in clinically unaffected newborns emerging from fetal distress, using H-Reflex.
METHODS
This cross-sectional study comprised 48 full-term newborn infants investigated between 8h and 10 days after birth. Twenty-one (21) had fetal distress defined
Developed in 1960s, cardiotocography is a screening test and fetal blood sampling (FBS) is an adjunctive, diagnostic technique to detect fetal hypoxia. A fetal blood sample pH value of less than 7.20 has a higher specificity than a pathological CTG to predict low Apgar score at 1 min. Though with a