glucosamine sulfate/back pain

BACKGROUND The underlying pathology and natural course of Modic changes (MC) in the vertebral body marrow and high intensity zones (HIZs) in the annulus fibrosus is not completely clarified. These findings on magnetic resonance imaging (MRI) have initiated different treatments with little or unclear

The concept of chronic nonspecific back pain (CNBP) as a pathology of the spine (osteochondrosis, spondylosis, intervertebral disc herniation, facet syndrome) is extremely outdated and has not justified itself, first of all, from the therapeutic view point. Numerous studies, including meta-analyzes

METHODS Laboratory based controlled in vivo study. OBJECTIVE To determine the in vivo effects of oral glucosamine sulfate on intervertebral disc degeneration. BACKGROUND Although glucosamine has demonstrated beneficial effect in articular cartilage, clinical benefit is uncertain. A Centers for