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hypothermia/obesity

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Ethanol-induced hypothermia and hyperglycemia in genetically obese mice.

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Blood glucose and rectal temperatures were monitored in two strains of genetically obese mice (C57 BL/6J ob/ob) prior to and following intragastric ethanol administration in an attempt to relate the hypothermic response to ethanol to extracellular glucose concentration. In contrast to expectation,
BACKGROUND Hypothermia is associated with an increased postoperative morbidity and mortality. Forced-air warming systems are the most effective methods for its prevention. When using a mattress, a reduction in the area of diffusion of warm air by crushing due to excess weight cannot be ruled

Hypothermia in insulin-treated obese rats.

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Changes of colonic temperature were investigated to examine a mechanism of hypothermia in the obese rats which received subcutaneous administration of intermediate type-insulin (8 U/day) for 8 weeks. Although diurnal rhythmicity of colonic temperature levels was maintained similarly with those of
Visceral fat adiposity plays an important role in the development of metabolic syndrome. We reported previously the impact of human visceral fat adiposity on gene expression profile of peripheral blood cells. Genes related to circadian rhythm were highly associated with visceral fat area and period

Development of the hypothermia in obese mice (genotype ob/ob).

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Heavier-obese mice (genotype, ob/ob) displayed their characteristic hypothermia at ambient temperatures and obese mice at all body weights did so after 60 min in the cold (3.0 - 5.5 degrees C). The fall in core temperature was least in slightly obese (3.5 degrees C) and greatest in extremely-obese
DL-alpha-methyl-p-tyrosine methyl ester hydrochloride affected the hyperphagia and hypothermia characteristic of the genetically obese mouse (genotype, ob/ob) throughout an experimental period of 5 days. Intraperitoneal injections of 100 mg/kg body weight, daily, resulted in a significant increase
BACKGROUND Obese Zucker rats demonstrate increased susceptibility to hepatic ischemia-reperfusion injury. This study evaluates the effect of mild systemic hypothermia on ischemia-induced acute fulminant necrosis during warm ischemia and reperfusion, and investigates blood metabolic profiles under
OBJECTIVE To evaluate the effect of anesthesia induced mild systemic hypothermia on hepatic injury in lean and obese rats during warm ischemia. BACKGROUND Hepatic warm ischemia during surgery remains a significant problem, particularly in organs with presumed baseline dysfunction. METHODS The left
OBJECTIVE To describe a patient positive for the anti-aquaporin 4 antibody with hypothalamic lesions showing hypothermia, hypotension, hypersomnia, and obesity. METHODS Case report. METHODS University hospital. METHODS We describe a 21-year-old woman who was positive for anti-aquaporin 4 antibody

Studies on hypothermia and thyroid function in the obese (ob/ob) mouse.

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Hypothermia associated with percutaneous nephrolithotomy.

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OBJECTIVE To characterize the perioperative fall in core body temperature associated with percutaneous nephrolithotomy, and to identify patients at greater risk of hypothermia. METHODS A retrospective review was undertaken of core body temperatures in 77 patients who underwent 95 percutaneous

Seasonal hypothermia in a large migrating bird: saving energy for fat deposition?

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We have tested the hypothesis that a large (2 kg) migratory bird, such as the barnacle goose Branta leucopsis, becomes hypothermic before its autumn migration, when food is not scarce, but when it is necessary to conserve and/or store energy in the form of fat. Abdominal temperature (T(ab)) was
OBJECTIVE To conduct a pilot trial of mild intraoperative hypothermia during cerebral aneurysm surgery. METHODS One hundred fourteen patients undergoing cerebral aneurysm clipping with (n = 52) (World Federation of Neurological Surgeons score < or =III) and without (n = 62) acute aneurysmal
Hypothalamic proopiomelanocortin (POMC) gene expression is reduced in many forms of obesity and diabetes, particularly in those attributable to deficiencies in leptin or its receptor. To assess the functional significance of POMC in mediating metabolic phenotypes associated with leptin deficiency,

Orexin turns up the heat on obesity.

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Brown adipocytes burn chemical energy to produce heat for protection against hypothermia and obesity. Sellayah et al. now reveal that a secreted neuropeptide, Orexin, functions a key driver of brown adipocyte differentiation through direct actions on brown adipose precursors.
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