indirubin/inflammation

BACKGROUND OF THE INVENTION Indirubin is extracted from the indigo plant. Indirubin is a constituent of a traditional Chinese herbal formula, Dang Gui Long Hui Wan used in the treatment of chronic myelogenous leukemia (CML). It has also been used in Asia as a systemic treatment for psoriasis. In

TECHNICAL FIELD The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration to a subject in need

TECHNICAL FIELD The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration to a subject in need

INCORPORATION-BY-REFERENCE OF MATERIAL ELECTRONICALLY FILED Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing submitted concurrently herewith and identified as follows: One 1,534 byte ASCII (text) file named "Seq_List" created on Mar. 8,

INCORPORATION-BY-REFERENCE OF MATERIAL ELECTRONICALLY FILED Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing submitted concurrently herewith and identified as follows: One 1,209 byte ASCII (text) file named "Seq_List" created on Dec. 20,

TECHNICAL FIELD The present invention is directed to a method for treating inflammatory arthritis in a mammal. The method comprises administering to a mammal a therapeutically effective amount of at least one compound selected from indigo, isoindigo, indirubin or derivatives thereof, such as

CROSS REFERENCE TO RELATED APPLICATIONS This application is a national phase filing under 35 U.S.C. 371 of International Application No. PCT/CN2014/000525, filed May 26, 2014, which claims priority to Chinese Patent Application No. CN201310202029.3, filed May 28, 2013, the disclosures of each of