l lactic acid/atrophy

Proper injection of poly-l-lactic acid has a role in avoiding development of subcutaneous papules. We evaluated the safety and efficacy of our injection technique ("cross-fanning") and compared it to 4 previous studies. Forty patients were evaluated for adverse events (bruising, edema, erythema,

Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients. Scarring may be pitted or hypertrophic in nature, although in most cases it is atrophic. Atrophic acne scarring follows dermal collagen and fat loss after moderate to severe acne

OBJECTIVE The aim of this study is to evaluate the toxicity of holmium-166 poly(L-lactic acid) microspheres administered into the hepatic artery in pigs. METHODS Healthy pigs (20-30 kg) were injected into the hepatic artery with holmium-165-loaded microspheres ((165)HoMS; n=5) or with

BACKGROUND Atrophic scars represent a loss of collagen and a challenging reconstructive dilemma with disappointing traditional treatments. OBJECTIVE To study the safety and efficacy of the treatment of atrophic scars using an ablative fractionated CO2 laser and topical poly-L-lactic acid (PLLA)

Porous titanium (pTi) can possess a low Young's modulus equal to that of human bone, depending on its porosity. However, the mechanical strength of pTi deteriorates greatly with increasing porosity. On the other hand, certain medical polymers exhibit biofunctionalities, which are not possessed

Achieving secure bony fixation of medial canthus is a challenge. We used a resorbable poly-L-lactic acid-polyglycolic acid screw (LactoSorb office fixation kit) in 5 cases: 2 with traumatic medial canthal dystopia, 1 with scleroderma and orbital fat atrophy causing malapposition of the medial

BACKGROUND Poly-L-lactic acid (PLLA) has been widely used in the enhancement of facial contours, but its use in nonfacial areas is rarely cited. OBJECTIVE To demonstrate the efficacy and safety of PLLA for neck and chest rejuvenation. METHODS Thirty-six patients with different degrees of cutaneous

The purpose of this study was to evaluate various types of meniscus scaffolds that mimic the meniscus structure, and to establish a novel cell-free meniscus scaffold with polyglycolic acid or poly-l-lactic acid. Four types of scaffolds were implanted into Japanese white rabbits: poly-l-lactic acid

Facial lipoatrophy is one of the complications of antiretroviral therapy in HIV+ patients. Poly-L-lactic-acid filling can compensate this atrophy. This treatment has been completely covered by social security since 2005. The filling technique is described in this article.

OBJECTIVE We performed a basic investigation using white rabbits of the sustained release and embolizing effects of poly L-lactic acid microspheres (PLA) to determine their usefulness for chemoembolization. METHODS Fifteen male Japanese white rabbits were used. Sustained release of an embolizing

Bevacizumab (Avastin(®)) has been used by ophthalmologists in many countries as an off-label drug for the treatment of wet age-related macular degeneration (AMD). Due to its short half-life necessitating frequent intravitreal injection, a method for sustained delivery is in need. We demonstrated

The objective of this study was to investigate the effects of dynamic loading on the in vitro degradation properties of poly(L-lactic acid)/beta-tricalcuim phosphate (PLLA/beta-TCP) composite scaffolds. These scaffolds were prepared by a technique, namely solvent self-proliferating/model

While intervertebral disc (IVD) degeneration is associated with the majority of cases of low back pain, current treatments are symptomatic rather than curative. Tissue engineering offers a treatment that both cures the problem of disc degeneration and restores normal disc function. One of the major

Osteosarcoma (OSA) is malignant bone tumor, occurring in children and adults, characterized by poor prognosis. Despite advances in chemotherapy and surgical techniques, the survival of osteosarcoma patients is not improving significantly. Currently, great efforts are taken to identify novel