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ligustrazine/hemorrhage

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文章臨床試驗專利權
9 結果
Astragalus membranaceus (Ast) and ligustrazine (Lig) have a protective effect on lower hemorrhagic transformation induced by pharmaceutical thrombolysis. The cerebral ischemia rat model was induced with autologous blood clot injections. A combination of Ast and Lig, or a protein kinase C
OBJECTIVE To assess the efficacy of Ligustrazine in combination with propranolol in the prevention of recurrent esophageal varices bleeding following liver cirrhosis, and its act mechanism. METHODS A prospective controlled study was conducted on 74 patients, in whom 38 belonged to treatment group,
OBJECTIVE To explore effects of ligustrazine injection (LI) on lymph circulation during the recovery of heamoregic shock. METHODS Effects of LI on lymph circulation were observed and determined in 16 Wistar rats by lymphatology methods. RESULTS During hemorrhagic shock, the intestinal lymph flux,
OBJECTIVE To explore the therapeutic mechanism of Salvia miltiorrhize, ligustrazine and Panax notoginseng in treating late hemorrhagic shock in rabbit. METHODS Rabbit hemorrhagic shock models (MPA 5.3 kPa) were set up according to Wiggers' method and administrated Salvia miltiorrhiza, ligustrazine,
BACKGROUND Haemorrhagic transformation is an asymptomatic event that frequently occurs after following ischaemic stroke, particularly when pharmaceutical thrombolysis is used. However, the mechanism responsible for haemorrhagic transformation remains unknown, and therapeutics have not been
OBJECTIVE To study the regulatory effect of Ligustrazine Injection (LI) on the cellular immune function in patients undergoing autologous blood transfusion (ABT). METHODS Enrolled were 60 patients scheduled for receiving selective lumbar surgery at the Department of Spinal Orthopedics, First

[Effect of ligustrazine on proliferative glomerulonephritis].

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OBJECTIVE To investigate the therapeutic effect of ligustrazine on proliferative nephritis. METHODS 45 patients with mesangial cell proliferation were randomly divided into two groups according to age, clinical manifestations and the pathological lesions. Steroid, cyclophosphamide, losartan and
OBJECTIVE To evaluate the protective effect of ligustrazine on T-lymphocyte immunity of patients undergoing autologous blood transfusion (ABT). METHODS Forty American Society of Anesthesiologist (ASA) I - II patients scheduled for receiving selective lumbar surgery, with pre-operational anticipatory

Ligustrazine inhibits platelet activation via suppression of the Akt pathway.

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Aberrant activation of platelets has a critical role in thrombotic vascular events, including atherosclerosis, arterial thrombosis and myocardial infarction. The process of platelet activation is associated with multiple intracellular signaling pathways, including the phosphoinositide 3‑kinase/AKT
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