menispermum myosotoides/tyrosine

Cultured roots of Menispermum dauricum, a rich source of the bisbenzylisoquinoline alkaloid dauricine (1), were fed with l-[U-(14)C] tyrosine, L-[3-(13)C] tyrosine, and [2-(13)C] tvramine independently, and the incorporation of possible early precursors into 1 was studied. The results demonstrated

The biosynthetic relationship between acutumine 1 and dechloroacutumine 2 was studied using (13)C-labeled tyrosine and (3)H-labeled 2 as tracers. (13)C-NMR spectra of (13)C-labeled 1 and 2 showed that the alkaloids, each composed of two molecules of tyrosine, are derived from the same biosynthetic