From the aerial parts of Pluchea symphytifolia, four known and two new caffeoylquinic acids, 1,3,4,5-tetra-O-caffeoylquinic acid and 1,3-di-O-[3,4,-bis-(3,4-dihydroxyphenyl)-cyclobutane-1,2-dicarbonyl]- 4,5-di-O-caffeoylquinic acid, and two flavonols were isolated and their structures elucidated by