peganum retusum/serotonin

A number of cell cultures of Peganum harmala were initiated to check for a correlation between the harman alkaloid content of seedlings and cell lines derived therefrom. Despite a poor correlation between callus or suspension culture lines and parent plants, the mean alkaloid contents of strains

Cell suspension cultures of P. HARMALA, unable to form serotonin DE-NOVO, hydroxylated fed tryptamine to serotonin independently of the growth cycle up to 20 mg per g dry mass per day. The best biotransformation yield of 80% was obtained with a high cell density (30 g fresh mass/100 ml) and a 5 mM