phenyl ether/cephaloziella massalongoi

Methyl 4-(geranyloxy)-3-hydroxybenzoate (6), previously unreported, has been identified from the New Zealand liverwort Trichocolea hatcheri. Four new related 3-hydroxybenzoates 7-10 were also found, with a carbonyl at C-5 of the geranyl group and various double bond arrangements. Two known geranyl

The incorporation of 13C labelled glucose into trichocolein, deoxytomentellin, trans-phytol and stigmasterol has been studied in axenic cultures of the liverwort Trichocolea tomentella. Quantitative 13C NMR spectroscopic analysis of the resulting labelling patterns showed that the isoprene units of

The main cytotoxic component in New Zealand collections of the liverwort Trichocolea mollissima was identified as methyl 4-[(5-oxogeranyl)oxy]-3-methoxybenzoate, a structure that has not been reported previously. Two double-bond isomers of this geranyl ether were present at lower levels.

The synthesis of three geranyl ethers, methyl 4-[(2E)-3, 7-dimethyl-5-oxo-2,6-octadienyloxy]-3-methoxybenzoate (1), methyl 4-[(2E)-3,7-dimethyl-2,6-octadienyloxy]-3-methoxybenzoate (2), and methyl 4-[(2E)-3,7-dimethyl-2,6-octadienyloxy]-3-hydroxybenzoate (3), previously isolated from New Zealand