Psyllium powder is used as the placebo. A member of the research staff will package and dispense L-alanine and placebo in similar containers. A standard measuring spoon will be provided to the subject for preparing the placebo solution. Subjects will mix the placebo in the beverage of their choice and consume this approximately 20 minutes before meals or snacks, in according with the dosing guidelines set for them by the dietitian.
Meal Placebo Breakfast * 1-2 scoops Snack * .5 - 1 scoop Lunch * 1-2 scoops Snack * .5 - 1 scoop Dinner * 1-2 scoops

L-alanine, USP (Spectrum® Chemicals and Laboratory Products, Gardena, CA) will be packaged and dispensed by one member of the research staff who will have no other role in the study. A one-month supply will be dispensed to the subjects.
Meal L-Alanine Breakfast * 1-2 scoops Snack * .5 - 1 scoop Lunch * 1-2 scoops Snack * .5 - 1 scoop Dinner * 1-2 scoops

Fructose Intolerance

Subjects will mix the placebo in the beverage of their choice and consume this approximately 20 minutes before meals or snacks, in according with the dosing guidelines set for them by the dietitian.

Placedo

Subjects will mix the alanine in the beverage of their choice and consume this approximately 20 minutes before meals or snacks, in according with the dosing guidelines set for them by the dietitian.

Alanine

Augusta University

Investigation of Supplemental L-alanine in the Management of Dietary Fructose Intolerance

Investigation of Supplemental L-alanine in the Management of Dietary Fructose Intolerance: a Double-blind, Randomized Study

Change in GI symptom score with alanine and placebo, when compared to the baseline

Estimated daily consumption of fructose during the alanine and placebo phases, when compared to the baseline using prospective food diaries

Changes in breath hydrogen and/or methane values with alanine and placebo when compared with to the baseline

Changes in SF-12 scores between and after baseline and placebo

In this group, the patients received 100mg ferrous succinate and 200mg vitamin C three times per day for 3-4 months

In this group, the patients received 100mg ferrous succinate three times per day for 3-4 months

In this group, the patients received 200mg ferrous succinate three times per day for 3-4 months

Anemia, Iron-Deficiency

As experimental group, when patients take the tablets of ferrous succinate, they also take vitamin C at the same time

ferrous succinate and vitamin C

As active comparator, patients take the tablets of ferrous succinate with normal dosage in clinical practice

ferrous succinate

As another active comparator, patients take the tablets of ferrous succinate with double dosage

Hushan Hospital

the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients

The Efficacy and Safety of Vitamin C for Iron Supplementation Therapy in Adult Patients With Iron Deficiency Anemia(IDA)

The increased levels of hemoglobin after receiving three different treatment regimens are evaluated in the second week

The increased levels of reticulocyte after receiving three different treatment regimens are evaluated in the second week

The increased levels of hemoglobin after receiving three different treatment regimens are evaluated in the fourth week

The increased levels of ferritin after receiving three different treatment regimens are evaluated in the eighth week

The incidence of adverse events every two weeks are assessed, the adverse events include bellyache, diarrhea, constipation, vomiting, nausea.

phenylalanine/diarrhea

Investigation of Supplemental L-alanine in the Management of Dietary Fructose Intolerance

the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients

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