piper umbellatum/止痛藥

Anti-inflammatory and analgesic activities as well as the median lethal dose (LD50) of water-ethanolic extract (PHE) of the aerial parts of Pothomorphe umbellata were evaluated in animal models. The ED(50) (oral) for the inhibition of carrageenan-induced rat paw edema assay was determined to be 550

Piper umbellatum is a plant currently utilized in traditional medicine as a sedative. Administered to rats by intraperitoneal injection, an aqueous extract of this plant brings about an ataxia with a decrease in the animal's watchfulness which lasts about 48 hours. Are also concomitant to this

OBJECTIVE This review assesses the botany, traditional medicinal uses, phytochemistry, pharmacology and toxicology of P. umbellatum. METHODS Information on P. umbellatum was gathered via the internet (using Scirus, Google Scholar, CAB-Abstracts, MedlinePlus, Embase, Scielo, and Web of Science) and