sparteine/stroke

The goal of this study was to characterize differences in contractile responsiveness to several potassium channel antagonists in vascular smooth muscle from stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar-Kyoto normotensive rats (WKY). Helically-cut strips of carotid arteries

We investigated the influence of an intoxication with sparteine (10 mg/kg X min i.v.) on heart rate, arterial blood pressure, cardiac output, stroke volume and total peripheral resistance in anesthetized rats. The leading feature of the cardiovascular activity of sparteine in rats was a strong

This study characterizes a cellular mechanism for oscillatory contractions induced by norepinephrine in vascular smooth muscle from spontaneously hypertensive stroke prone rats (SHRSP). Helically cut strips of tail arteries from SHRSP and normotensive Wistar-Kyoto rats (WKY) were mounted in a muscle