tripalmitin/obesity

OBJECTIVE Long-term exposure of beta cells to lipids, particularly saturated fatty acids in vitro, results in cellular dysfunction and apoptosis (lipotoxicity); this could contribute to obesity-related diabetes. Our aims were to relate cell death to intracellular triglyceride concentration,

In order to develop a simple and accurate screening test for steatorrhea, the authors compared quantitative stool fat excretion with breath excretion of 14CO2 after the ingestion of 14C-labeled trioctanoin, tripalmitin, or triolein. The study group included 24 nonobese subjects without steatorrhea

To determine the relative rates of lipid metabolism in muscle and adipose tissues in obesity, we measured uptake and oxidation of free palmitate or tripalmitin into tissue slices in vitro. We also measured lipoprotein lipase (LPL) activity of soleus muscle and perirenal adipose tissues. Muscle took