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Hemorrhagic shock has been shown to alter bone marrow (BM) myelopoiesis. Isolated hemorrhagic shock is uncommon after trauma and the combined effect of tissue injury and shock on myelopoiesis is unknown. We studied the growth of BM granulocyte-macrophage colony forming units (CFU-GM) following shock
Turpentine is an oleoresin obtained from various species of pine. In turpentine poisoning, various signs and symptoms of toxicity may develop, including hematuria, renal failure, loss of vision, chest pain, vomiting, severe coughing, gastroesophageal hemorrhage, hypotension, swelling of the throat
1. When toxic filtrates from cultures of B coli, B. typhosus, or meningococci are injected into the blood stream, peritoneal cavity, or subcutaneous tissue of tuberculous guinea pigs, the skin at the site of a tuberculin reaction becomes hemorrhagic. The extent of the hemorrhage is proportional to
Fibrinogen synthesis was measured by the [14C]carbonate method in isolated rat livers perfused with blood from normal rats and rats injected with turpentine 1, 5, and 16 hr before bleeding. Five- and 16-hr blood increased synthesis 2-fold, compared with normal and 1-hr blood. Turpentine injection
Severe arterial bleeding must have been a common, much feared and often fatal complication of trauma since man appeared on Earth. The early surgeons would have used direct pressure on the wound, which would only have provided temporary relief, or learned to apply a tight dressing. If it was an
A 15-year-old girl presented with a chief complaint of bleeding from her nose. She had noticed worms emerging from her right nostril. She had a continuous dull ache on the right side of her nose, spreading over the maxillary sinus area, and on the infra-orbital margin on the same side. She
When blood plasma proteins are depleted by bleeding, with return of washed red cells (plasmapheresis), it is possible to bring dogs to a steady state of low plasma protein in the circulation and a uniform plasma protein production on a basal diet. Such dogs become test subjects by which the effect
Lucio phenomenon (LP) or erythema necroticans is a relatively rare, peculiar reaction pattern occurring in untreated lepromatous (LL) or borderline lepromatous (BL) leprosy cases. A 38-year-old male, a cook by occupation, was referred to the dermatology clinic from otolaryngology department with
OBJECTIVE
The binding of sweet-tasting compounds in a human (Mcg) Bence-Jones dimer has been characterized by x-ray crystallography. Aspartame binding in this immunoglobulin fragment is remarkable. Unexpected pain relief noted by A.B.E., a crystallographer with diagnosed osteoarthritis, suggested
Plasmids containing cottontail rabbit papillomavirus (CRPV) DNA can induce papillomas in vivo, but efficiency has been low. The aim of the present investigation was to explore some of the technical variables involved in inoculation of rabbits with recombinant CRPV DNA in attempts to improve both
Suction with a partial vacuum of -70 mm. Hg applied to normal skin of rabbits causes intracutaneous hemorrhage after an average time of 8 minutes. Inflammation produced by various agents, including turpentine, killed streptococci, staphylococci, pneumococci or meningococci, and filtrates from
A phenomenon of local skin reactivity to B. typhosus culture filtrates is described in this report. The reactivity was induced by skin injections of the filtrate followed 24 hours later by an intravenous injection of the same filtrate. The local response consisted of severe hemorrhagic necrosis and
Normal red blood cells in dogs contain stroma in fairly uniform amounts. This red cell stroma is rich in proteins and lipides. Anemia due to blood loss causes an increase in stroma protein. The highest levels of stroma protein are found in the severe anemias. As the anemia is corrected by red cell
Oxygen-derived free radicals may play an important role in the pathogenesis of organ injury and death following hemorrhagic shock. This study was designed to test the effects of Polyethylene Glycol-Superoxide Dismutase (PEG-SOD) on gastric mucosal injury and survival in an animal model of