Probiotics will be given to women included in study arm

Probiotics

Each subject provided morning stool and venous blood ubes) specimens at three time-points, i.e. at baseline (before probiotic administration), after probiotic administration (VSL#3®, one capsule twice a day) for 4 weeks, and at 4 weeks after stopping the probiotic intake. Each capsule contained approximately 112.5 billion live freeze-dried bacteria (a mixture of eight species -- Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, and Lactobacillus delbrueckii), which had been stored at 2-4ºC till ingestion.

Probiotic (VSL#3)

Effect of Probiotic Administration on Gut Flora Composition

Change in Human Gut Flora and in Immune Functions Following Probiotic Administration

To determine the profile of gut flora (% abundance of various bacterial phyla, families, genera and species) in healthy Indian women, using a metagenomic technique (sequencing of V3 region of 16S ribosomal RNA).

To determine the effect of administration of a probiotic preparation for a 4-week period on the profile of gut flora in healthy Indian women.

To assess the effect of probiotic administration on immune responses, and the persistence of such changes on discontinuation of probiotic administration

To determine whether the changes in gut flora after probiotic administration persist after discontinuation of such administration (at 4 weeks after such discontinuation)

vaginitis/obesity

Effect of Probiotic Administration on Gut Flora Composition

科學支持的最完整的草藥數據庫