The present invention relates to non-cytotoxic fusion proteins, and to the use thereof as therapeutics for suppressing conditions such as mucus hypersecretion, inflammation, neuroendocrine disorders, and neuroendocrine tumours.
Non-cytotoxic proteases are a discrete group of proteases, which act on
BACKGROUND
The present application encompasses proteins and peptide fragments of those proteins, which are produced by proteolytic digestion of the proteins, and which both proteins and peptide fragments are useful for diagnosing of cancer or for monitoring for the presence of cancer in an
REFERENCE TO SEQUENCE LISTING
This application contains a Sequence Listing submitted as an electronic text file named "14fpo.sub.--03.sub.--009_ST25.txt", having a size in bytes of 2 KB, and created on Apr. 18, 2014. The information contained in this electronic file is hereby incorporated by
BACKGROUND
Field of Invention
This present application encompasses proteins and peptide fragments of those proteins produced by proteolytic digestion that are useful for diagnosing or monitoring for the presence of cancer in an individual.
Description of the Related Art
Screening mammograms
The present invention relates to the suppression of the growth, maintenance, and progression of common cancers, in particular colorectal, prostate, breast and lung cancers.
Colorectal cancer is the third most common cancer in both men and women in the United States, according to the World Health
Pursuant to the provisions of 37 C.F.R. .sctn. 1.52(e)(5), the sequence listing text file named 98374_Seq_Listing.txt, created on Apr. 9, 2014 and having a size of 652,334 bytes, and which is being submitted herewith, is incorporated by reference herein in its entirety.
The present invention relates
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