proline/inflammation

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Methods of treating pain and inflammation with proline

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BRIEF SUMMARY OF THE INVENTION The invention relates to the use of proline and/or 4-hydroxyproline as therapeutic agents, especially for the treatment for wounds as well as inflammation and/or pain. The invention also relates to pharmaceutical compositions comprising proline and/or 4-hydroxyproline

Aprepitant L-proline solvates--compositions and cocrystals

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FIELD OF THE INVENTION The invention relates to a new aprepritant compositions and crystalline compounds containing aprepitant. More particularly, the invention relates to solvated aprepitant L-proline solvate compositions, aprepitant L-proline solvate cocrystals, therapeutic uses of the aprepitant

Aprepitant L-proline composition and cocrystal

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FIELD OF THE INVENTION The invention relates to a new aprepitant composition and a crystalline compound containing aprepitant, more particularly, the invention relates to an aprepitant L-proline composition, an aprepitant L-proline cocrystal, therapeutic uses of the aprepitant L-proline or the

Proline substituted cyclosporin analogues

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TECHNICAL FIELD The present invention relates to novel cyclosporin analogues, compositions containing them, processes for their preparation, intermediates in their synthesis, and their use as therapeutics for prevention of organ transplantation rejection, the treatment of immune disorders and

Pipecolic acid derivatives of proline threonine amides useful for the treatment of rheumatoid arthritis

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FIELD OF THE INVENTION Non-peptidic compounds are described for treatment of autoimmune diseases. Of particular interest are pipecolic acid derivatives compounds incorporating a characterizing segment condensed from pipecolic acid, aspartic acid, proline and threonine, or derivatives thereof, which

Method for treating inflammatory diseases by administering a thrombin inhibitor

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BACKGROUND OF THE INVENTION This invention relates to methods for treating inflammatory diseases by administration of a thrombin inhibitor. Anti-inflammatory drugs include non steroidal anti-inflammatory drugs (NSAIDs) which exert anti-inflammatory, analgesic and antipyretic activity. These include

Methods and compositions for modulating C5-a-mediated inflammatory responses

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BACKGROUND OF THE INVENTION Complement anaphylatoxin C5a is a 74-amino acid peptide generated from the fifth component of complement (C5) during complement activation (Ember et al., Immunopharmacology 38:3, 1997; Gerard, Annu Rev Immunol. 12:775, 1994). C5a acts efficiently as an anaphylatoxin

Anti-inflammatory peptides, and uses thereof

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CROSS REFERENCE TO RELATED APPLICATIONS This application is a 371 National Phase Entry of International Patent Application No. PCT/EP2016/067090 filed on Jul. 18, 2016 which claims benefit under 35 U.S.C. .sctn. 119(b) of EP Application No. 15177013.8 filed Jul. 16, 2015 and EP Application No.

Antipyretic and anti-inflammatory lys pro val compositions and method of use

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a new pharmaceutical composition useful for the treatment of pyrexia and inflammation. More particularly, this invention relates to a tripeptide sequence contained in alpha-Melanocyte Stimulating Hormone and ACTH which

Antipyretic and anti-inflammatory peptides

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1. FIELD OF THE INVENTION This invention relates to a new pharmaceutical composition useful for the treatment of pyrexia and inflammation. More particularly, this invention relates to a tripeptide sequence contained in alpha-Melanocyte Stimulating Hormone and ACTH which has been identified as an

Pro-inflammatory fibrinopeptide

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REFERENCE TO SEQUENCE LISTING The present application incorporates by reference SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 and SEQ ID NO: 4 provided herewith on a diskette, created on Jan. 11, 2005 and containing 5,979 bytes. The information recorded on the diskette is identical to the written

Peptides which stimulate the expression of the cytokines of inflammation and promote tissue regeneration

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FIELD OF THE INVENTION This invention concerns a new family of peptide molecules having the capacity especially of stimulating the expression of the cytokines of inflammation and promoting regeneration of tissues. The invention, thus, also pertains to pharmaceutical compositions containing at least

Proline phosphonate derivatives

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a novel class of peptidyl derivatives of aromatic diesters of .alpha.-aminoalkylphosphonic acids useful for selectively inhibiting elastase, selectively inhibiting chymotrypsin-like enzymes, selectively inhibiting

Peptides having anti-cancer and anti-inflammatory activity

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TECHNICAL FIELD The present invention relates to the fields of cancer treatment, inflammatory disease, and peptide chemistry. BACKGROUND The amino acid sequence Leu-pro-pro-ser-arg (SEQ ID NO:1) is a known immunostimulant and is described in papers by W. Weigle and is the subject of a US Patent.

N-acetyl-L-hydroxy-proline zinc salt

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BACKGROUND OF THE INVENTION Diseases affecting the connective tissues of the body have been the subject of a great deal of investigation for the past two decades. The essential amino acid L-hydroxyproline is an important constituent of proteins, particularly those proteins comprising the connective

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