coronaridine/ervatamia

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Tumor inhibitors. II. Alkaloids of Ervatamia dichotoma. Isolation, crystallization, and pharmacological properties of coronaridine.

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A new indole alkaloid from Ervatamia yunnanensis.

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The stems of Ervatamia yunnanensis have afforded a new indole alkaloid, ervataine (1), whose structure was determined by spectroscopic analysis. Five known compounds, ibogaine (2) coronaridine (3), heyneanine (4), voacangine hydroxyindolenine (5) and coronaridine hydroxyindolenine (6), were also

Ervatamia coronaria: chemical constituents and some pharmacological activities.

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A new bisindole alkaloid, 19,20-dihydroervahanine A was isolated from the stems of Ervatamia coronaria grown in Brazil, together with five known alkaloids: coronaridine, heyneanine, voacristine, voacamine, descarbomethoxyvoacamine and five phenolic acids: vanillic, gentisic, syringic,

Monomeric Indole Alkaloids from Ervatamia hainanensis.

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Eleven monomeric indole alkaloids have been isolated from the roots of Ervatamia hainanensis. Nine of them are known: coronaridine 1, coronaridine hydroxyindolenine 2, heyneanine 3, vobasine 4, perivine 5, ibogamine 6, geissoschizol 7, 10-hydroxygeissoschizol 8 and 3-oxocoronaridine 9; and two are

[Study on chemical constituents in rhigome of Ervatamia hainanensis].

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OBJECTIVE To investigate the chemical constituents of the rhizome of Ervatamia hainanensis. METHODS The solvent extraction and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physico chemical properties and spectra

[Studies on alkaloids from Ervatamia pandacaqui].

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To inverstigate the alkaloids from the twigs and leaves of Ervatamia pandacaqui, eleven known alkaloids were isolated by silica gel, Sephadex LH-20, and ODS column chromatography, as well as RP-HPLC. Their structures were elucidated by UV, IR, MS, and NMR spectral data as coronaridine (1),

Analgesic components from bornean medicinal plants, Tabernaemontana pauciflora Blume and Tabernaemontana pandacaqui Poir.

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The analgesic components were isolated from a Bornean medicinal plant, Tabernaemontana pauciflora Blume (syn. Ervatamia blumeana Mark gr.), and the major components were identified as coronaridine and 3-(2-oxopropyl)coronaridine. Four minor components were estimated to be 5R- and

Heyneanine hydroxyindolenine, a new indole alkaloid from Ervatamia coronaria var. plena.

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The whole plant of Ervatamia coronaria var. plena obtained from Thailand has afforded a new indole alkaloid 19S-heyneanine hydroxyindolenine whose structure was deduced through interpretation of spectral data. Nine known alkaloids, coronaridine, coronaridine hydroxyindolenine, voacangine, voacangine

Ibogan, Aspidosperman, Vincamine, and Bisindole Alkaloids from a Malayan Tabernaemontana corymbosa: Iboga Alkaloids with C-20α Substitution.

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Ten new indole alkaloids (1-10) comprising five ibogan, two aspidosperman, one vincamine, and two bisindole alkaloids, in addition to 32 known alkaloids, were isolated from the stem-bark extract of a Malayan Tabernaemontana corymbosa. The structures of these alkaloids were determined based on

Bioactivity-guided isolation of cytotoxic constituents from three medicinal plants.

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BACKGROUND The ethanol extracts and their fractions of three Indian medicinal plants, Ervatamia coronaria (Jacq.) Stapf, (Apocynaceae), Mimosa pudica L. (Mimosaceae) and Caesalpinia bonduc (L.) Roxb. (Caesalpiniaceae) were tested for their cytotoxic activity in the brine shrimp lethality (BSL)

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