European Journal of Medicinal Chemistry 2008-Nov
Chemotherapy of leishmaniasis part-VIII: synthesis and bioevaluation of novel chalcones.
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Abstrakt
Some novel dihydro-alpha-ionone based chalcones have been synthesized and evaluated for their in vitro antileishmanial activity in promastigote and amastigote model. Some of the compounds showed 100% inhibition at 5 and 2 microm/ml concentration.